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Activation of a Cl--secretory response in NCM460 immortalized human colonic cells

✍ Scribed by Jones, Heather M.; Moyer, Mary Pat; Lance, Peter; Duffey, Michael E.

Book ID: 122581114
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 176 KB
Volume: 118
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(00)84564-3

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## Abstract Neurotensin (NT) is a highly expressed gastrointestinal (GI) neuropeptide, which modulates GI motility, secretion and cell growth as well as intestinal inflammation. Since EGF receptor is highly expressed in human colon cancer cells, we sought to examine whether NT stimulation contribut