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Activation mechanisms of PIP5K isozymes by the small GTPase ARF6

✍ Scribed by Yuji Funakoshi; Hiroshi Hasegawa; Yasunori Kanaho


Book ID
113419013
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
376 KB
Volume
50
Category
Article
ISSN
0065-2571

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Regulation of PIP5K activity by Arf6 and
✍ Yuji Funakoshi; Hiroshi Hasegawa; Yasunori Kanaho πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 171 KB

## Abstract The phospholipid kinase phosphatidylinositol 4‐phosphate 5‐kinase (PIP5K) catalyzes the phosphorylation of the membrane phospholipid phosphatidylinositol 4‐phosphate to generate the pleiotropic phospholipid phosphatidylinositol 4,5‐bisphosphate [PI(4,5)P~2~]. To date, three mammalian PI