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Activation induces rapid and profound alterations in the trafficking of T cells

✍ Scribed by Alf Hamann; Katja Klugewitz; Frank Austrup; Dorothee Jablonski-Westrich

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
266 KB
Volume
30
Category
Article
ISSN
0014-2980

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## Abstract We have previously shown that intraspinal microinjection of lysophosphatidylcholine (LPC), a potent demyelinating agent, results in a rapid but brief influx of T cells (between 6 and 12 h). This is accompanied by a robust activation of macrophages/microglia that leads to demyelination b