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Activation-induced upregulation of inhibitory killer Ig-like receptors is regulated by protein kinase C

✍ Scribed by Chwae, Yong-Joon; Lee, Jae Myun; Kim, Eun Joon; Lee, Seung Tae; Soh, Jae-Won; Kim, Jongsun


Book ID
110041385
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
335 KB
Volume
85
Category
Article
ISSN
0818-9641

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HeLa cell spreading on a gelatin substrate requires the activation of protein kinase C (PKC), which occurs as a result of cell-attachment-induced activation of phospholipase A2 (PLA2) to produce arachidonic acid (AA) and metabolism of AA by lipoxyginase (LOX). The present study examines how PKC acti