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Activation and regioselectivity of five-membered cyclic thionocarbamates to nucleophilic attack

โœ Scribed by Awheda, Ismail; Saygili, Nezire; Garner, A. Christopher; Wallis, John D.


Book ID
121374873
Publisher
The Royal Society of Chemistry
Year
2013
Tongue
English
Weight
725 KB
Volume
3
Category
Article
ISSN
2046-2069

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Relationship between regioselective redu
โœ Margaret M. Kayser; Peter Morand ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 186 KB

It has been demonstrated that the reduction of a carbonyl function with LiAlH4 is catalyzed by Li+ cation 132 and that stereoselection is fixed from the first step in the mechanism, namely, association of Li+ cation with the oxygen atom of the carbonyl function3. The subsequent addition of AlH4nucle