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Activation and proliferation signals in mouse B cells VIII. Induction of DNA synthesis in B cells by a combination of calcium ionophores and phorbol myristate acetate

✍ Scribed by Gerry G. B. Klaus; Anne O'Garra; Martin K. Bijsterbosch; Mary Holman


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
616 KB
Volume
16
Category
Article
ISSN
0014-2980

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The transcriptional regulation of the fibronectin (FN) gene in hepatoma cells by phorbol myristate acetate (PMA) was investigated. PMA increased the synthesis and mRNA levels of FN and its promoter activity in Hep3B hepatoma cells. The PMA-induced activation of FN expression was blocked by a protein