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Activation and Inhibition of Endogenous Matrix Metalloproteinases in Articular Cartilage: Effects on Composition and Biophysical Properties

✍ Scribed by Lawrence J. Bonassar; Jennifer L. Stinn; Claribel G. Paguio; Eliot H. Frank; Vernon L. Moore; Michael W. Lark; John D. Sandy; Anthony P. Hollander; A.Robin Poole; Alan J. Grodzinsky


Book ID
115566231
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
229 KB
Volume
333
Category
Article
ISSN
0003-9861

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In vivo effects of naproxen on compositi
✍ Dr. Anthony Ratcliffee; Walid Azzo; Fatemeh Saed-Nejad; Nancy Lane; Melvin P. Ro πŸ“‚ Article πŸ“… 1993 πŸ› Elsevier Science 🌐 English βš– 859 KB

## Abstract Naproxen is a nonsteroidal anti‐inflammatory drug commonly used in the clinical treatment of joint disease. In this study, its effect in vivo on the biochemical composition, metabolic activities, and metalloproteinase activities of normal canine articular cartilage was analyzed. The art