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Activating and inhibitory FcγRs in autoimmune disorders

✍ Scribed by Nimmerjahn, Falk


Book ID
113028128
Publisher
Springer
Year
2006
Tongue
English
Weight
458 KB
Volume
28
Category
Article
ISSN
0344-4325

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Activating and inhibitory Fcγ receptors
✍ Mirentxu I. Iruretagoyena; Claudia A. Riedel; Eduardo D. Leiva; Miguel A. Gutiér 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 359 KB

## Abstract The molecular bases responsible for the loss of T cell tolerance to myelin antigens leading to the onset of multiple sclerosis remain obscure. It has been shown that balanced signaling through activating and inhibitory receptors is critical for the maintenance of tolerance to self antig