Bordetella pertussis toxin (PTX), a key component of acellular pertussis vaccines, is known to be endowed with adjuvant properties. In experiments designed to get insights into the interactions between PTX and circulating immune cells, we first observed that addition of PTX to adult whole blood indu
✦ LIBER ✦
Activated T killer cells induce apoptosis in lung epithelial cells and the release of pro-inflammatory cytokine TNF-α
✍ Scribed by Toshifumi Shinbori; Henning Walczak; Peter H. Krammer
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 294 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0014-2980
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## Abstract Adoptive cell therapy involving the use of __ex vivo__ generated cytokine‐induced killer cells (CIKs) provides a promising approach to immunotherapy. However, the therapeutic activity of CIKs is limited by the immunosuppressive factors active in the host. It has become increasingly appa