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Activated ras and ret oncogenes induce over-expression of c-met (hepatocyte growth factor receptor) in human thyroid epithelial cells

✍ Scribed by Ivan, Mircea; Bond, Jane A; Prat, Maria; Comoglio, Paolo Maria; Wynford-Thomas, David


Book ID
110060699
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
768 KB
Volume
14
Category
Article
ISSN
0950-9232

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## Abstract Spontaneously immortalized human mammary epithelial cells MCF‐IOA were transfected with an activated c‐Ha‐ras oncogene. Transfected cells (MCF‐IOT) acquire a malignant pheno‐type, as already reported. Studies of l‐2′‐deoxyuridine incorporation in cultures given graded doses of hydrocort