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Activated protein C attenuates cardiopulmonary bypass–induced acute lung injury through the regulation of neutrophil activation

✍ Scribed by Sachiko Yamazaki; Syunji Inamori; Takeshi Nakatani; Michiharu Suga

Book ID
113763997
Publisher
CTSNet
Year
2011
Tongue
English
Weight
677 KB
Volume
141
Category
Article
ISSN
1097-685X

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✍ Y Yamaguchi; N Hisama; K Okajima; M Uchiba; K Murakami; Y Takahashi; S Yamada; K 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 271 KB 👁 2 views

We investigated the role of anticoagulant in the ischemia/reperfusion injury of the liver, using activated protein C (APC), active human urinary thrombomodulin (UTM), and factor Xa blocked at the active site (DEGR-Xa). Liver ischemia was induced in male Wistar rats by occlusion of the portal vein wi