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Activated Notch2 Signaling Inhibits Differentiation of Cerebellar Granule Neuron Precursors by Maintaining Proliferation

✍ Scribed by David J. Solecki; XiaoLin Liu; Toshifumi Tomoda; Yin Fang; Mary E. Hatten

Book ID: 117607862
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 468 KB
Volume: 31
Category: Article
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(01)00395-6

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## Abstract Multiple studies have shown that migration, proliferation, and differentiation of oligodendrocyte (OL) lineage cells are influenced by fibroblast growth factor‐2 (FGF‐2) signaling through its receptors (FGFR) FGFR‐1, FGFR‐2, and FGFR‐3. We report the effectiveness and specificity of a u