Role of mast cell activation in inducing
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Hongbin Yuan; Xiaoling Zhu; Shuangqiong Zhou; Qianbo Chen; Xiaoxing Zhu; Xue Ma;
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Article
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2009
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John Wiley and Sons
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English
β 223 KB
## Abstract The brainβderived neurotrophic factor (BDNF) plays a critical role in pain hypersensitivity. BDNF is the ligand of P2X4 receptors (P2X4R) in the microglia. The causative factors involving the P2X4R over expression in the microglia remains unclear. Mast cell activation has a close relati