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Activated B Cells Mediate Efficient Expansion of Rare Antigen-Specific T Cells

โœ Scribed by Caroline Zentz; Martina Wiesner; Stephen Man; Bernhard Frankenberger; Barbara Wollenberg; Peter Hillemanns; Reinhard Zeidler; Wolfgang Hammerschmidt; Andreas Moosmann

Book ID
116531439
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
855 KB
Volume
68
Category
Article
ISSN
0198-8859

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Adoptive transfer of in vitro generated antigen-specific T cells has been successfully used to treat viral infections in immunodeficient patients. Therefore, methods for the rapid in vitro expansion of antigen-specific T cells are needed. Influenza virus efficiently infects dendritic cells, and pept