## Abstract Cembranoids are cyclic diterpenoids found in tobacco and in marine invertebrates. The present study established that tobacco cembranoids inhibit behavioral sensitization to nicotine in rats and block several types of nicotine acetylcholine receptors (AChRs). 1) At the behavioral level,
Actions of octocoral and tobacco cembranoids on nicotinic receptors
✍ Scribed by P.A. Ferchmin; Oné R. Pagán; Henning Ulrich; Ada C. Szeto; Richard M. Hann; Vesna A. Eterović
- Book ID
- 116922414
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 327 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0041-0101
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## Abstract Nicotine has been reported to be neuroprotective in experimental and epidemiological studies. In addition to nicotine, tobacco and cigarette smoke contain cembranoids, which are antagonists of neuronal nicotinic receptors (nAChR). Exposure of hippocampal slices to __N__‐methyl‐D‐asparta