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Actions of novel agonists, antagonists and antipsychotic agents at recombinant rat 5-HT6 receptors: A comparative study of coupling to Gαs

✍ Scribed by Delphine S. Dupuis; Clotilde Mannoury la Cour; Christine Chaput; Laurence Verrièle; Gilbert Lavielle; Mark J. Millan


Book ID
113587617
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
589 KB
Volume
588
Category
Article
ISSN
0014-2999

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Herein, we evaluate the interaction of the ␣ 2 -AR antagonist, yohimbine, as compared to fluparoxan, at multiple monoaminergic receptors and examine their roles in the modulation of adrenergic, dopaminergic and serotonergic transmission in freelymoving rats. Yohimbine displays marked affinity at hum