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Actions of Avermectin Analogs on γ-Aminobutyric Acid (GABA)-Sensitive and GABA-Insensitive Chloride Channels in Mouse Brain

✍ Scribed by G.T. Payne; D.M. Soderlund


Book ID
115642694
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
452 KB
Volume
47
Category
Article
ISSN
0048-3575

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✍ Abalis, Ibrahim M. ;Eldefrawi, Amira T. ;Eldefrawi, Mohyee E. 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 729 KB

The interaction of avermectin B1, (AVM) with the y-aminobutyric acid (GABA) receptor of rat brain was studied using radioactive ligand binding and tracer ion flux assays. Avermectin potentiated the binding of [3Hlflunitrazepam and inhibited the binding of both [3H]muscimol and [35Slf-butylbicyclopho