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Actions of 8-hydroxy-2-(N-dipropylamino) tetralin (8-OH-DPAT) at α2-adrenoceptors

✍ Scribed by Borton, Meriel ;Connaughton, Sonia ;Docherty, J. R.


Book ID
111197392
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
512 KB
Volume
11
Category
Article
ISSN
0144-1795

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Synthesis of R-(+)- and S-(−)-8-hydroxy-
✍ M. J. Ackland; L. G. Dring; J. R. Jones; N. Gilon 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 364 KB

## Abstract The title compounds were synthesised in 7 steps from 1,7‐dihydroxynaphthalene as follows: 1,7‐dihydroxynaphthalene was methylated and subjected to a Birch reduction to yield 8‐methoxy‐2‐tetralone. Reductive amination with sodium cyanoboro[^3^H]hydride and n‐propylamine gave 8‐methoxy‐2‐