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Actions of 4-methyl-2-aminopyridine on neuromuscular transmission and contractility of skeletal muscle

✍ Scribed by N. Kiloh; A.L. Harvey; W.E. Glover


Book ID
115876763
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
354 KB
Volume
70
Category
Article
ISSN
0014-2999

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Facilitatory effects of 4-aminopyridine
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## Abstract The effects of 4‐aminopyridine (4‐AP) on neuromuscular transmission were studied in vitro in the rat flexor digitorum longus muscles. 4‐AP produced dose‐dependent increases in endplate potential (EPP) amplitude, in rise time to peak, and in the average number of acetylcholine quanta rel