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Action of Reserpine on Isolated Intestinal Muscle

✍ Scribed by GILLIS, C. N.; LEWIS, J. J.


Book ID
109592880
Publisher
Nature Publishing Group
Year
1957
Tongue
English
Weight
94 KB
Volume
179
Category
Article
ISSN
0028-0836

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The patch-clamp method has been used to investigate the action of caffeine on the calcium current (Ic,) in single isolated smooth muscle cells of the guineapig ileum. Caffeine (10 mM) substantially inhibited Ic,. This effect occurred in a biphasic manner and it was not due either to activation of ad