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Action of protein kinase inhibitors on calcium current in intestinal smooth muscle cells

✍ Scribed by A.V. Zima; A.E. Belevich

Book ID
119180035
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
131 KB
Volume
31
Category
Article
ISSN
1043-6618

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The inhibitory action of caffeine on cal
The inhibitory action of caffeine on calcium currents in isolated intestinal smooth muscle cells
✍ A. V. Zholos; L. V. Baidan; M. F. Shuba πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 820 KB

The patch-clamp method has been used to investigate the action of caffeine on the calcium current (Ic,) in single isolated smooth muscle cells of the guineapig ileum. Caffeine (10 mM) substantially inhibited Ic,. This effect occurred in a biphasic manner and it was not due either to activation of ad