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Action of potassium amide on 6-substituted derivatives of 2-bromopyridine in liquid ammonia

✍ Scribed by J. W. Streef; H. J. den Hertog

Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
877 KB
Volume
88
Category
Article
ISSN
0165-0513

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## Abstract Reaction of 6‐chloro‐ and 6‐(methylthio)purine with potassium amide in liquid ammonia leads to the formation of adenine. When these aminations are carried out with ^15^N‐labelled potassium amide, the ^15^N label is found to be present in the amino group, proving that these reactions do