Antitubercular drugs in general are given in various combinations, one being isoniazid and thiacetazone. In the present study, was evaluated the in vivo chromosome-damaging effects of a combination of these two drugs in 72 h lymphocyte cultures. Chromosome aberrations were significantly increased in
Action of hydroxyurea on chromosome physiology in Rhynchosciara angelae
β Scribed by G. M. Machado-Santelli; R. Basile
- Publisher
- Springer Netherlands
- Year
- 1978
- Tongue
- English
- Weight
- 544 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0016-6707
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The mutagenic action of mitomycin C (MMC) on the chromosomes of two reconstructed karyotypes of barley was studied. MMC-induced chromatid aberrations were found to be distributed non-randomly along the chromosomes. The regions situated next to the secondary constrictions of chromosomes 6 and 7 appea
This paper describes a novel biochemical effect of 1 -P-D-arabinofuranosylcytosine (Ara-C), a potent antitumor agent, on the process of DNA replication in cultures of human lymphoblasts (CCRF-CEM). By using short incubation periods of five minutes with 3H-thymidine and analyzing the nascent DNA by v