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Action of fluoride on cholinesterase—II: In vitro reactivation of cholinesterases inhibited by organophosphorous compounds

✍ Scribed by Edith Heilbronn


Book ID
115768898
Publisher
Elsevier Science
Year
1965
Tongue
English
Weight
714 KB
Volume
14
Category
Article
ISSN
0006-2952

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Effect of diisopropylphosphorofiuoridate (DFP), an irreversible cholinesterase (ChE) inhibitor, on compound action potential (CAP) of sciatic nerve in vitro was examined. Further, the role of cholinesterase reactivator ( 1 acetyl-4-hydroxy imino methyl pyridinium bromide; SPK-3) in reversing DFP-ind