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Action of detergents on 3H-dihydroergokriptine binding and localization of α-adrenoceptors in synaptosomal membranes

✍ Scribed by Jose S. Aguilar; Manuel Criado; E. De Robertis

Book ID
115876206
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
538 KB
Volume
61
Category
Article
ISSN
0014-2999

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Action of detergents and pre- and postsy
Action of detergents and pre- and postsynaptic localization of3H-naloxone binding in synaptosomal membranes. A structural approach
✍ Criado, Manuel ;Aguilar, Jos� S. ;de Robertis, E. 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 590 KB

## Abstract ^3^H‐naloxone specific binding was carried out on synaptosomal membranes isolated from basal ganglia of the cat brain. A high‐ and a low‐affinity site with __Kd__~1~ = 3.7 n__M__ and __Kd__~2~ = 35 n__M__ having __B__~max 1~ = 79 pmole/g protein and __B__~max 2~ = 224 pmole/g protein we