Action de la rubratoxine B sur la respiration des mitochondries hépatiques de rat

✍ Scribed by C. Bernard; P. Dumas

• Book ID: 104781055
• Publisher: Springer Netherlands
• Year: 1975
• Tongue: English
• Weight: 189 KB
• Volume: 55
• Category: Article
• ISSN: 0301-486X
• DOI: 10.1007/bf00467092

✦ Synopsis

The in vitro effect of rubratoxin B on the electron transport system of rat liver mitochondira was investigated. This mycotoxin depressed oxygen consumption in ADP-lacking mitochondira and in ADP-coupled mitochondria, using succinate or beta-hydroxybutyrate as substrats. Rubratoxin B is neither an oxidative-phosphorylation inhibitor nor uncoupling agent. Its effect is compared with aflatoxin B1.