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Actinomycin D-induced apoptosis involves the potassium channel Kv1.3

✍ Scribed by Jürgen Bock; Ildikò Szabó; Andreas Jekle; Erich Gulbins

Book ID
117052167
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
295 KB
Volume
295
Category
Article
ISSN
0006-291X

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✍ Jenny Lam; Heike Wulff 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 213 KB

## Abstract The voltage‐gated Kv1.3 and the calcium‐activated KCa3.1 potassium channel modulate many calcium‐dependent cellular processes in immune cells, including T‐cell activation and proliferation and have therefore been proposed as novel therapeutic targets for immunomodulation. Kv1.3 is highl