Uridine metabolism has an important role in the physiopathology of the nervous system. In this paper, we have explored the effects of exogenous uridine on LAN-5 human neuroblastoma cells. Cells were exposed to uridine for 4 days and cell proliferation, neurite outgrowth, and 160 kDa neurofilament (N
✦ LIBER ✦
Actinomycin D decreases protein kinase C content and induces neuritogenesis in neuroblastoma cells
✍ Scribed by Maria-Dolores Miñana; Vicente Felipo; Santiago Grisolía
- Book ID
- 115924623
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 356 KB
- Volume
- 280
- Category
- Article
- ISSN
- 0014-5793
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Acrylonitrile (ACN) is classified by IARC as a probable carcinogen. Chronic exposure to ACN increases the incidence of tumors in various organs of test animals, including the brain and lung. ERK1/2 activation plays crucial roles in cell proliferation and is involved in many steps of tumor progressio