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Actinomycin D complexes with oligonucleotides as models for the binding of the drug to DNA. Paramagnetic induced relaxation experiments on drug-nucleic acid complexes

✍ Scribed by Chiao, Yu-Chih Chen; Krugh, Thomas R.

Book ID: 126272845
Publisher: American Chemical Society
Year: 1977
Tongue: English
Weight: 959 KB
Volume: 16
Category: Article
ISSN: 0006-2960
DOI: 10.1021/bi00623a029

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## Abstract Fluorescence, CD, absorption, and ^1^H‐nmr studies are reported for complexes of 7‐amino‐actinomycin D with deoxydinucleotides, deoxytetranucleotides, and poly(__d__G‐__d__C)· poly(__d__G‐__d__C). The optical spectra for the 7‐amino‐actinomycin D complex with p__d__G‐__d__C, p__d__G‐__d

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