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Actinomycin D-associated lesions mimicking DNA-DNA interstrand crosslinks detected by alkaline elution in cultured mammalian cells

โœ Scribed by Joan M.K. Fox; Timothy D. Byrne; William G. Woods

Book ID
115778463
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
654 KB
Volume
34
Category
Article
ISSN
0006-2952

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โœ Jeffrey R. Hincks; Roger A. Coulombe Jr. ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 616 KB

Alkaline elution is a sensitive and commonly used technique to detect cellular DNA damage in the form of DNA strand breaks and DNA cross-links. Conventional alkaline elution procedures have extensive equipment requirements and are tedious to perform. Our laboratory recently presented a rapid, simpli