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Actin out with filamin: Two sides of the story

โœ Scribed by Jianjun Hu; Volney Sheen

Book ID
102262140
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
82 KB
Volume
33
Category
Article
ISSN
1059-7794

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โœฆ Synopsis

Mutations in the filamin B

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Disease-associated mutations in the acti
Disease-associated mutations in the actin-binding domain of filamin B cause cytoplasmic focal accumulations correlating with disease severity
โœ Philip B. Daniel; Tim Morgan; Yasemin Alanay; Emilia Bijlsma; Tae-Joon Cho; Trev ๐Ÿ“‚ Article ๐Ÿ“… 2012 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 399 KB ๐Ÿ‘ 1 views

ABD mutations demonstrated that with only one exception disease-associated substitutions, surrounding hinge 1 demonstrated no tendency to form actin-filamin foci. The exception, a substitution in filamin repeat 6, lies within a region previously implicated in filamin-actin binding. These data are co