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Actin-linked regulation of the human platelet contractile system

✍ Scribed by Isaac Cohen; Elizabeth Kamanski; Andre De Vries

Book ID
115904066
Publisher
Elsevier Science
Year
1973
Tongue
English
Weight
381 KB
Volume
34
Category
Article
ISSN
0014-5793

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Caldesmon was originally purified from gizzard smooth muscle as a major calmodulin-binding protein which also interacts with actin filaments. It has an alternative binding ability to either calmodulin or actin filaments depending upon the concentration of Ca2+ ("flip-flop binding"). Two forms of cal