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Actephilol A and epiactephilol A: two novel aromatic terpenoids isolated from Actephila excelsa

✍ Scribed by Simon P.B Ovenden; Alex L.S Yew; Robert P Glover; Siewbee Ng; Christine J Rossant; Jacinto C Regalado Jr.; Doel D Soejarto; Antony D Buss; Mark S Butler


Book ID
104231676
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
85 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis


An investigation into the chemical constituents of a crude MeOH extract from a specimen of Actephila excelsa (family Euphorbiaceae), led to the isolation of two new epimeric aromatic terpenoids, actephilol A 1 and epiactephilol A 2. The gross structures and relative stereochemistry of 1 and 2 were determined through extensive 2D NMR analysis.


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## Abstract Henrycinols A (**1**) and B (**2**), two novel indole alkaloids, together with three known compounds, (+)‐Δ^14^‐vincamine (**3**), (+)‐16‐epi‐Δ^14^‐vincamine (**4**), and (+)‐isoeburnamine (**5**), were isolated from the roots of __Melodinus henryi__ Craib. Their structures were establi