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Acrylonitrile-induced toxicity and oxidative stress in isolated rat colonocytes

โœ Scribed by Ahmed M. Mohamadin; Ebtehal El-Demerdash; Hesham A. El-Beshbishy; Ashraf B. Abdel-Naim

Book ID
116454333
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
299 KB
Volume
19
Category
Article
ISSN
1382-6689

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## Abstract Acrylonitrile (ACN) is a volatile, toxic liquid used as a monomer in the manufacture of synthetic rubber, styrene plastics, acrylic fiber, and adhesives. ACN is a potent neurotoxin. A role for free radical mediated lipid peroxidation in the toxicity of ACN has been suggested. We examine