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Acrylamide-regulated neurofilament expression in rat pheochromocytoma cells

โœ Scribed by Weiquan W Lin; Marvin A Friedman; Xiao-Fan Wang; Mohamed B Abou-Donia

Book ID
114005430
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
428 KB
Volume
852
Category
Article
ISSN
0006-8993

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## Abstract We found that ebselen [2โ€phenylโ€1,2โ€benzisoselenazolโ€3(2H)โ€one] caused phosphorylation of mitogenโ€activated protein kinase (MAPK), followed by expression of neurofilamentโ€M, a neuronโ€specific protein, in cultured PC12 rat pheochromocytoma cells. The ebselenโ€induced MAPK activation was s