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Acrosin, the peculiar sperm-specific serine protease

✍ Scribed by Uwe Klemm; Werner Müller-Esterl; Wolfgang Engel

Book ID
104661272
Publisher
Springer
Year
1991
Tongue
English
Weight
772 KB
Volume
87
Category
Article
ISSN
0340-6717

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✦ Synopsis

The sperm enzyme acrosin has long been known as one of the key enzymes in the mammalian fertilization process. Elucidation of primary structures of preproacrosin from various species have allowed a deeper insight into the structural organization and the complex evolution of the sperm proteinase acrosin. In addition to the typical elements of serine proteases, the acrosin molecule possesses one novel domain that might convey DNA-binding properties.

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