Acremoxanthones A and B, novel antibiotic polyketides from the fungus Acremonium sp. BCC 31806

✍ Scribed by Masahiko Isaka; Somporn Palasarn; Patchanee Auncharoen; Somjit Komwijit; E.B. Gareth Jones

• Book ID: 104095995
• Publisher: Elsevier Science
• Year: 2009
• Tongue: French
• Weight: 188 KB
• Volume: 50
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2008.10.146

✦ Synopsis

Acremoxanthones A and B, novel anthraquinone-xanthone heterodimers with a unique linkage pattern, together with two known compounds, acremonidins A and C, were isolated from the fungus Acremonium sp. BCC 31806. The structures of the acremoxanthones were determined by analysis of 2D NMR and mass spectrometric data. Acremoxanthones and acremonidins exhibited antibacterial, antifungal, antiplasmodial, and cytotoxic activities.