## Abstract Cholangiocarcinoma (CCA) induced by liver fluke (__Opisthorchis viverrini__, Ov) infection is one of the most common and serious disease in northeast Thailand. To elucidate the molecular mechanism of cholangiocarcinogenesis induced by Ov infection, we employed a hamster model of CCA ind
Acquired resistance to Opisthorchis viverrini in the hamster
β Scribed by David J. Flavell
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 269 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0035-9203
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## Abstract Synergy between exposure to chemical carcinogens (nitrosamines) and infestation with the liver fluke __Opisthorchis viverrini__ has been demonstrated in a hamster model of hepatocarcinogenesis (Flavell et al., Carcinogenesis 4:927β930, 1983; Thamavit et al., Carcinogenesis 8:1351β1353,
## Abstract Inflammationβmediated DNA damage triggered by __Opisthorchis viverrini__ (OV) infection is a major risk factor of cholangiocarcinoma (CCA). We have recently reported that nitrative and oxidative DNA damage participates in CCA development caused by repeated infection with OV [Pinlaor __e