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Acquired alpha-2-antiplasmin deficiency in acute promyelocytic leukaemia

✍ Scribed by Giuseppe Avvisati; Jan W. Ten Cate; Augueste Sturk; Roy Lamping; Maria C. Petti; Franco Mandelli

Book ID
114711373
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
583 KB
Volume
70
Category
Article
ISSN
0007-1048

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## Abstract Bleeding diathesis and a hyper‐fibrinolytic state often accompany a diagnosis of Acute Promyelocytic Leukaemia (APML). This complication can have grave effects if not successfully treated, with a 10–20% incidence of haemorrhagic death. We hypothesized that α‐2‐antiplasmin levels would c