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Acotiamide (Z-338) as a possible candidate for the treatment of functional dyspepsia

✍ Scribed by H. Suzuki; T. Hibi


Book ID
110851909
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
489 KB
Volume
22
Category
Article
ISSN
1350-1925

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Mechanism for distribution of acotiamide
✍ Kazuyoshi Yoshii; Masamichi Hirayama; Toshifumi Nakamura; Ryoko Toda; Junko Hase πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 280 KB

The novel gastroprokinetic agent acotiamide improves gastric motility by inhibiting acetylcholinesterase activity in stomach; however, the mechanism of distribution of acotiamide from blood to stomach has not been clarified. Here, the tissue distribution of acotiamide was investigated in rats. The t