Mechanism for distribution of acotiamide
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Kazuyoshi Yoshii; Masamichi Hirayama; Toshifumi Nakamura; Ryoko Toda; Junko Hase
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Article
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2011
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John Wiley and Sons
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English
β 280 KB
The novel gastroprokinetic agent acotiamide improves gastric motility by inhibiting acetylcholinesterase activity in stomach; however, the mechanism of distribution of acotiamide from blood to stomach has not been clarified. Here, the tissue distribution of acotiamide was investigated in rats. The t