✦ LIBER ✦

ACK1 tyrosine kinase: Targeted inhibition to block cancer cell proliferation

✍ Scribed by Mahajan, Kiran; Mahajan, Nupam P.

Book ID: 120415938
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 650 KB
Volume: 338
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2013.04.004

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Breast cancer cell line proliferation bl

Breast cancer cell line proliferation blocked by the Src-related Rak tyrosine kinase

✍ Tanya Meyer; LiHui Xu; Jinli Chang; Edison T. Liu; Rolf J. Craven; William G. Ca 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 564 KB

## Abstract Rak is a 54 kDa protein tyrosine kinase originally isolated from breast cancer cells and expressed in epithelial cells. It resembles the protooncogene __Src__ structurally but lacks an amino‐terminal myristylation site and localizes to the nuclear and perinuclear regions of the cell. We

Targeting cyclin B1 inhibits proliferati

Targeting cyclin B1 inhibits proliferation and sensitizes breast cancer cells to taxol

✍ Ilija Androic; Andrea Krämer; Ruilan Yan; Franz Rödel; Regine Gätje; Manfred Kau 📂 Article 📅 2008 🏛 BioMed Central 🌐 English ⚖ 926 KB

Targeted inhibition of the epidermal gro

Targeted inhibition of the epidermal growth factor receptor-tyrosine kinase by ZD1839 (‘Iressa’) induces cell-cycle arrest and inhibits proliferation in prostate cancer cells

✍ Alessandro Sgambato; Andrea Camerini; Beatrice Faraglia; Raffaele Ardito; Gabrie 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 297 KB 👁 2 views

## Abstract The epidermal growth factor (EGF) plays a role in the development of prostate cancer, which becomes essential after androgen resistance has emerged. The EGF receptor (EGFR) is therefore a potential target for anticancer therapy. We evaluated the effects of ZD1839 (‘Iressa’), an orally a

The dietary flavonoid luteolin inhibits

The dietary flavonoid luteolin inhibits Aurora B kinase activity and blocks proliferation of cancer cells

✍ Fang Xie; Qingyu Lang; Mei Zhou; Haoxing Zhang; Zhishun Zhang; Yifeng Zhang; Bo 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 853 KB

Inhibition of Syk protein tyrosine kinas

Inhibition of Syk protein tyrosine kinase induces apoptosis and blocks proliferation in T-cell non-Hodgkin's lymphoma cell lines

✍ Wilcox, R A; Sun, D X; Novak, A; Dogan, A; Ansell, S M; Feldman, A L 📂 Article 📅 2009 🏛 Nature Publishing Group 🌐 English ⚖ 208 KB

Drug Resistance in Cancer Cells || Mecha

Drug Resistance in Cancer Cells || Mechanisms of Resistance to Targeted Tyrosine Kinase Inhibitors

✍ Siddik, Zahid H.; Mehta, Kapil 📂 Article 📅 2009 🏛 Springer US 🌐 English ⚖ 663 KB

It was estimated that in 2008, 1,437,180 patients would receive a new cancer diagnosisand 565,650individualswould die of cancer (Jemal et al. 2008).Since the vast majority of patients dying of cancer will have had anticancer therapy, both c- ventional chemotherapy and novel targeted therapy, it can