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Acidosis modifies metabolic functions but does not affect vascular resistances in perfused rat livers

✍ Scribed by Catherine M Pastor; Antoine Hadengue


Book ID
119525474
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
176 KB
Volume
34
Category
Article
ISSN
0168-8278

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Uptake, metabolism and biliary elimination of infused cysteinyl leukotrienes were investigated in single-pass perfused rat liver. Hypoxia did not impair uptake of infused [3H]leukotriene C4, but inhibited biliary excretion of radioactivity by about 50% compared with normoxic control experiments. In