Acidity and metal (Mg2+, Ca2+, Zn2+) affinity of l-γ-carboxyglutamic acid and its peptide analog
✍ Scribed by Remko, Milan; Broer, Ria; Remková, Anna; Van Duijnen, Piet Th.
- Book ID
- 126968510
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 408 KB
- Volume
- 614
- Category
- Article
- ISSN
- 0009-2614
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📜 SIMILAR VOLUMES
By condensing diethyl ethoxymethylenemalonate with diethyl acetamidomalonate, 5-hydroxy-2,4-dicarbethoxypyrrole was prepared. Hydrogenation over Pt-C to 5-oxo-2,4-dicarbethoxypyrrolidine, followed by alkaline hydrolysis gave y-carboxyglutamate. Mild alkaline hydrolysis yielded 5-oxo-2,4-pyrrolidine
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