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Acidic pH enhances structure and structural stability of the capsid protein of hepatitis E virus

✍ Scribed by Mohammad Zafrullah; Zenab Khursheed; Sushma Yadav; Deepak Sahgal; Shahid Jameel; Faizan Ahmad

Book ID
116287590
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
245 KB
Volume
313
Category
Article
ISSN
0006-291X

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The hepatitis C virus (HCV) envelope glycoprotein E1 has been widely employed as a potential vaccine antigen in clinical research. A truncated form (amino acids 192-326) of the E1 protein (E1y) was expressed in the yeast Hansenula polymorpha and purified from the cell lysate. E1y forms protein parti