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Acid-mediated regioselective alkylation of 1,2,3-triazole

✍ Scribed by Andrei O. Korenm


Publisher
Journal of Heterocyclic Chemistry
Year
2002
Tongue
English
Weight
22 KB
Volume
39
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

1,2,3‐Triazole reacts with isopropyl alcohol in concentrated sulfuric acid to yield 1‐isopropyl‐1__H__‐1,2,3‐triazole as the only reaction product.


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ChemInform Abstract: Alkylation and Acyl
✍ S. OHTA; I. KAWASAKI; T. UEMURA; M. YAMASHITA; T. YOSHIOKA; S. YAMAGUCHI πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 32 KB πŸ‘ 1 views

Alkylation and Acylation of the 1,2,3-Triazole Ring. -General procedures for the regioselective synthesis of 1-alkyl (cf. ( III)), 1,5-disubstituted (cf. (V), (VI), (VIII)), and 1,4-disubstituted 1,2,3-triazoles (cf. (XII)) are developed.