Acid dissociation constants of phenylalkanolamines
β Scribed by S. Riegelman; L. A. Strait; E. Z. Fischer
- Publisher
- John Wiley and Sons
- Year
- 1962
- Tongue
- English
- Weight
- 420 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The biopharmaceutical profile of a compound depends directly on the dissociation constants of its acidic and basic groups. We estimate these constants using kernel ridge regression and graph kernels. The performance of our approach is similar to that of a semiβempirical model (Tehan et
R~suMI?~. -La variation de la (( constante de dissociatioii )) des acide5 macromoleculaires polybasiques en fonction du degre de neutralisation, de la dilution dc l'acide et de la teneur en electrolyte de la solution est expliquee par la presence d'une charge negative sur la macromolrkule. Par l'att