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Achalasia sicca-juvenile Sjögren's syndrome with achalasia and gastric hyposecretion

✍ Scribed by S. Similä; J. Kokkonen; M. Kaski

Publisher
Springer
Year
1978
Tongue
English
Weight
905 KB
Volume
129
Category
Article
ISSN
0340-6997

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✦ Synopsis

Sjögren's syndrome (SS) in its classical form, which includes keratoconjunctivitis sicca, xerostomia and recurrent enlargement of the salivary glands, is associated with a connective tissue disease in at least half the patients. According to the present study of three patients with SS, achalasia and gastric hyposecretion seem to be either further manifestations of SS, or separate phenomena associated with SS. The gastric hyposecretion involves both the hydrochloric acid and the total volume of the secretion, but the gastric mucosa has a normal appearance on microscopy. Because of the simultaneous presence of achalasia, gastric hyposecretion and reduced salivation, we have called the combination "achalasia sicca". The reduction in the secretions of the upper gastrointestinal tract might have a pathogenic association with achalasia.

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