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Acetylcholine Receptor-specific T Cells Are Present in the Normal Immune Repertoire: A Study with Recombinant Polypeptides of the Human Acetylcholine Receptor α-Subunit

✍ Scribed by A. MELMS; G. MALCHEREK; R. SCHOEPFER; N. SOMMER; H. KALBACHER; J. LINDSTROM


Book ID
119868533
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
162 KB
Volume
681
Category
Article
ISSN
0890-6564

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T cells from normal and myasthenic indiv
✍ Dr A. Melms; G. Malcherek; U. Gern; H. Wiethölter; C. A. Müller; R. Schoepfer; J 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 846 KB

The a-subunit of the nicotinic acetylcholine receptor is the major target of the autoimmune response in myasthenia gravis. We investigated the proliferative response of T cells from patients with myasthenia gravis and healthy volunteers to recombinant polypeptides of the human acetylcholine receptor