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Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

✍ Scribed by Sang-Won Min; Seo-Hyun Cho; Yungui Zhou; Sebastian Schroeder; Vahram Haroutunian; William W. Seeley; Eric J. Huang; Yong Shen; Eliezer Masliah; Chandrani Mukherjee; David Meyers; Philip A. Cole; Melanie Ott; Li Gan

Book ID
116783657
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
35 KB
Volume
68
Category
Article
ISSN
0896-6273

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Two factors potentially determining the consistent overexpression of sialyl-Le x antigen in colon carcinoma and metastases were investigated: (i) the expression of the mucins MUC1 and MUC2, known to carry sialyl-Le x , by Northern blotting; (ii) the extent of sialic acid O-acetylation, by Western bl