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Acetylation of Tat Defines a CyclinT1-Independent Step in HIV Transactivation

✍ Scribed by Katrin Kaehlcke; Alexander Dorr; Claudia Hetzer-Egger; Veronique Kiermer; Peter Henklein; Martina Schnoelzer; Erwann Loret; Philip A. Cole; Eric Verdin; Melanie Ott

Book ID
117737177
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
435 KB
Volume
12
Category
Article
ISSN
1097-2765

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## Abstract ## Background Retroviral transduction of cells is improved upon virus adsorption onto immobilized fibronectin (FN) fragments. Because HIV‐1 Tat possesses the same functional domains that lead to increased transduction efficiency in FN by colocalization of bound virus and cells, we hypo